The alternative text for this image may have been generated using AI. Here, we review the recent advances in designing, constructing, refining and applying synthetic genomes. First, we cover genome ...

Since the discovery of the double-helical structure of DNA and postulation of the central dogma of molecular biology, stating that the flow of genetic information goes from DNA to RNA to protein, the ...

DNA synthesis is vital to several processes in biopharmaceutical innovation, including the development of gene therapies, CRISPR gene editing, antisense oligonucleotides and RNA therapies. The need ...

DNA is the raw material of modern medicine yet is the only part of drug development not accessible at the lab bench. DNA synthesis, the first step in most biological workflows including gene synthesis ...

Matthew Hayes (Left) is the Chief Technology Officer and founder at Evonetix, a groundbreaking gene synthesis technology company created in 2015, where he deploys his expertise in multi-disciplinary ...

From synthetic biology and gene therapy to data storage and biofuel production, the demand for synthetic DNA is rising. (1) Chemicals remove the 5’-hydroxyl protecting group. The nucleosides are rich ...

Launched in 1990, The Human Genome Project was a monumental effort to sequence and analyze the entire human genome to understand how genetics influence health. While the Human Genome Project helped ...

While DNA microarrays are already widely used, adapting the technology to RNA microarrays has proved difficult due to the lower stability of RNA. In 2018, the University of Vienna demonstrated how ...

A full-size, high-density RNA microchip is about the size of a fingernail and can contain up to 780 000 unique RNA sequences, each occupying a ~14 x 14 μm² area. The presence and the quality of the ...