The proper use of spike-in normalization in ChIP-seq improves sensitivity for detecting genome-wide changes between conditions, but improper use is common, calling some biological conclusions into ...

Solid tumors are complex entities that actively shape their microenvironment to create a supportive environment for their own growth. Angiogenesis and immune suppression are two key characteristics of ...

To some extent, many organizations, if not all, suffer from some form of performance deviation. This can manifest itself in any goal or standard against which organizations may measure themselves.

Dr. James McCaffrey of Microsoft Research uses a full code sample and screenshots to show how to programmatically normalize numeric data for use in a machine learning system such as a deep neural ...

We collected a unique pair of microRNA sequencing data sets for the same set of tumor samples; one data set was collected with and the other without uniform handling and balanced design. The former ...