RNA-Seq and gene expression microarrays provide comprehensive profiles of gene activity, but lack of reproducibility has hindered their application. A key challenge in the data analysis is the ...

The proper use of spike-in normalization in ChIP-seq improves sensitivity for detecting genome-wide changes between conditions, but improper use is common, calling some biological conclusions into ...

Dr. James McCaffrey of Microsoft Research uses a full code sample and screenshots to show how to programmatically normalize numeric data for use in a machine learning system such as a deep neural ...