The localized loss of sensation with resultant reduction in pain stimuli is the end result of local anesthesia. This mode of anesthesia is considered to be safer than general anesthesia, because it ...

Although the mechanisms by which anesthetic drugs induce the state of general anesthesia have been considered one of the biggest mysteries of modern medicine and science, new research is deciphering ...

Despite decades of common use for surgeries of all kinds, the precise mechanism through which general anesthesia works on the body remains a mystery. New research investigated the common anesthetic ...

Scientists from Scripps Research have shown how anesthetics cause clusters of lipids in the cell membrane to break apart, triggering downstream processes that lead to a loss of consciousness. Share on ...

In a paper recently published in Neuron, researchers from the group of Botond Roska at IOB reveal how different cell types in cortex change their activity during general anesthesia, helping to ...

(A) Schematic diagram of the experimental system that detects calcium release from the endoplasmic reticulum by each ryanodine receptor. (B) Isoflurane selectively activates RyR1 (mean ± standard ...

CAMBRIDGE, MA -- Nitrous oxide, commonly known as "laughing gas," has been used in anesthesiology practice since the 1800s, but the way it works to create altered states is not well understood. In a ...

Mechanical embolectomy performed with general instead of local anesthesia is associated with worse clinical outcomes and poorer survival, according to an article published online March 25, 2014, ahead ...

Local anesthesia prevents pain during procedures by blocking nerves from transmitting pain signals to the brain. The effects of local anesthetic are short-lived, so healthcare teams primarily use it ...