A cancer drug class best known for attacking tumors may also help your immune system remember them better. Researchers at ...

The capacity of an organism to regenerate depends on cell dedifferentiation followed by proliferation. Mammals, in general, have limited regenerative capacity. Now, a team of researchers at the Salk ...

For all they do for us, our hearts aren't very good at repairing themselves. So when a person suffers a heart attack, their blood pump is left with a large amount of scar tissue, which can impede the ...

Researchers have identified key factors that promote the reprogramming of human stem cells to the naïve state, which can be used to model the earliest stages of development. This new knowledge will ...

A new way of reprogramming our immune cells to shrink or kill off cancer cells has been shown to work in the otherwise hard to treat and devastating skin cancer, melanoma. The discovery demonstrates a ...

Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and ...

Most tissues in the body can regenerate themselves after an injury, but unfortunately heart muscle cells aren’t one of them. Now, scientists at the Max Planck Institute have shown in mice that ...

"Cellular reprogramming could, in theory, allow us to control the activity and appearance of any cell," says Colas. "This concept has huge implications in terms of helping the body regenerate itself, ...

In order to reprogram readily available cells into specific immune cells that fight various diseases, one must know the “recipe” for the transformation. Researchers at Lund University have now created ...

Metabolic reprogramming in fibrotic lung diseases involves key metabolites like lactate, succinate, and 2-hydroxyglutarate, driving inflammation and fibroblast activation. Lactate accumulation ...